Peplo · Reconstitution calculator
BPC-157
Synthetic pentadecapeptide derived from a gastric juice protein; studied for soft-tissue, tendon, and GI healing.
healingReconstitution calculator
The total peptide in the vial — the mg number on the label (e.g. 5 mg). This is your whole supply, not one dose.
The sterile water you add to dissolve the powder (this is called reconstituting). More water makes small doses easier to measure.
How much you take in one injection. 1 mg = 1000 mcg.
Draw to 20 units
0.20 mL on a U-100 insulin syringe
A starting reference, not medical advice — see how we source this.
- Half-life
- ~0.5 h
- Route
- SubQ
- Storage
- Refrigerated 2-8°C; use within ~30 days (~30 days)
- Citations
- 15 referenced
US regulatory status
Not approved by the FDA for human use; sold and used as a research compound.
What is BPC-157?
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a protein found in gastric juice. It has been studied primarily in preclinical (animal) models for soft-tissue, tendon, and gastrointestinal repair.
How BPC-157 works
Promotes angiogenesis, modulates nitric oxide signalling, and upregulates growth-factor pathways involved in tissue repair.
What the research says
Animal studies have examined tendon-to-bone healing, angiogenesis, and gastrointestinal protection, and a 2025 systematic review summarized its use across orthopaedic sports-medicine research. See the references below for primary sources.
- 1999Osteogenic effect of a gastric pentadecapeptide, BPC-157, on the healing of segmental bone defect in rabbits
- 2009Modulatory effect of gastric pentadecapeptide BPC 157 on angiogenesis in muscle and tendon healing
- 2011The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration
- 2014Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts
- 2016Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications
- 2017Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation
- 2019Stable Gastric Pentadecapeptide BPC 157, Robert's Stomach Cytoprotection/Adaptive Cytoprotection Revisited
- 2020Modulatory effects of BPC 157 on vasomotor tone and the Src-Cav-1-eNOS signaling pathway in rats
- 2020Preclinical safety evaluation of body protective compound-157, a potential drug for treating various wounds
- 2021Stable Gastric Pentadecapeptide BPC 157 as a Therapy for the Disable Myotendinous Junctions in Rats
- 2022Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs
- 2022Pentadecapeptide BPC 157 and the central nervous system
- 2025Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review
- 2025Multifunctionality and Possible Medical Application of the BPC 157 Peptide
- 2025Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study
Evidence limitations
The literature is largely preclinical, and robust human clinical trials remain limited.
Safety & use boundary
BPC-157 is a research compound and is not approved for human use; its human safety profile is not well characterized. This page is educational and is not medical advice — consult a qualified clinician before making any health decision.
Published protocols
Dosing figures reported in the cited research. Educational reference, not a recommendation.
- 2011 study
recovery
250–500 mcg, once daily
- 2011 study
injury-repair
500–750 mcg, twice daily
- 2018 study
longevity
200–300 mcg, once daily
- 2011 study
cognitive
250–500 mcg, twice daily
How to reconstitute BPC-157
New to this? Here's the whole process, start to finish. Educational only — not medical advice.
What you'll need
- The BPC-157 vial — a small glass vial of white, freeze-dried powder
- Bacteriostatic water — the liquid you mix in (not plain sterile or tap water)
- U-100 insulin syringes — the small syringes marked in units
- Alcohol swabs to wipe the vial tops before you touch them with a needle
- A spot in the fridge to keep it once it's mixed
Step by step
Wipe everything down
Swab the rubber top of both the peptide vial and the bacteriostatic water with an alcohol wipe. Clean tops are what keep the mixed solution good for weeks instead of days.
Draw the water
Use the calculator above to see how much bacteriostatic water to add for your vial size. Pull exactly that amount out of the water vial with a syringe.
Add it slowly
Push the needle into the peptide vial and let the water run gently down the inside glass wall — don't blast it straight onto the powder.
Let it dissolve
Swirl the vial gently or just let it sit. The powder goes into solution on its own in a minute or two. Never shake it hard.
Read your draw
Enter your vial size, the water you added, and your dose in the calculator. It shows the exact units to pull into your syringe — you never do the math yourself.
Store it cold
Cap it and keep it in the fridge. BPC-157 stays good for about 30 days once it's mixed.
Reading your dose
The calculator gives you a number like “Draw to 20 units.” Units are just the numbered marks on a U-100 insulin syringe (100 units fill 1 mL). “20 units” means pull the plunger back to the 20 mark. You don't convert milligrams to micrograms in your head — that's the whole point of the calculator. If you're brand new to injecting, learn proper technique and site rotation from a qualified clinician or nurse before your first dose; this page covers the mixing and measuring, not the injection itself.
Storing it
Before mixing: Refrigerated; stable at room temp for short shipping windows Once reconstituted: Refrigerated 2-8°C; use within ~30 days (about 30 days). Don't freeze a reconstituted vial.
What “cycling” means
Many peptides are used in “cycles” — a stretch of daily or weekly use (“on”), then a break (“off”), rather than continuously. Cycling gives the body a rest and is a common pattern in the research. Any specific on/off lengths for a compound live in its published protocols above, drawn from the cited studies — this site shows you what the research used, it doesn't recommend a schedule for you.
Which form do you have?
BPC-157 is sold in more than one form — each is used differently.
- Injectable vial
- Ships as a freeze-dried powder you reconstitute with bacteriostatic water and draw on a U-100 insulin syringe — the reconstitution steps above walk through it.
- Capsule (oral)
- Taken by mouth — no mixing and no syringe. Follow the product's own labeling for the capsule strength and how many to take.
Common first-timer mistakes
Shaking the vial to mix it
Swirl it gently or just let it sit. Shaking can damage delicate peptides — you want the powder to dissolve, not foam.
Using tap water or plain sterile water
Use bacteriostatic water. Plain sterile water has no preservative, so a mixed vial spoils in a day or two instead of lasting weeks.
Leaving a mixed vial on the counter
Keep reconstituted vials in the fridge. Heat and light break the peptide down faster.
Eyeballing the dose instead of measuring
Use the calculator and draw to the exact unit mark on the syringe. Guessing a tiny volume is where most measuring errors happen.
Reusing needles
Use a fresh syringe each time. A used needle is duller, hurts more, and is no longer sterile.
Mixing up mg and mcg
1 mg = 1000 mcg. The calculator keeps them straight so you don't have to — just enter your dose in the unit it asks for.
Words you'll see
- Reconstitution
- Mixing a freeze-dried peptide powder with liquid (bacteriostatic water) so it can be drawn into a syringe.
- Bacteriostatic water
- Sterile water with a tiny amount of benzyl alcohol that stops bacteria growing, so a mixed vial keeps for weeks. Not the same as plain sterile water.
- U-100 insulin syringe
- A small syringe marked in “units,” where 100 units = 1 mL. Peptide draws are measured in these units.
- Subcutaneous (SubQ)
- An injection into the fatty layer just under the skin, rather than into muscle or a vein.
- mcg vs mg
- 1 mg = 1000 mcg. Doses are often written in micrograms (mcg); the calculator handles the conversion for you.
- Lyophilized
- Freeze-dried. The powder in the vial is the peptide with its water removed so it stays stable on the shelf.
- Half-life
- Roughly how long it takes your body to clear half of a dose — a rough sense of how long it stays active.
Common questions
What is BPC-157?
Synthetic pentadecapeptide derived from a gastric juice protein; studied for soft-tissue, tendon, and GI healing. Promotes angiogenesis, modulates nitric oxide signalling, and upregulates growth-factor pathways involved in tissue repair.
How is BPC-157 reconstituted?
BPC-157 ships as a lyophilised powder and is reconstituted with bacteriostatic water before use, then drawn on an insulin syringe. Use the calculator above to see the exact units to draw for your vial size and dose. This is a reference tool, not medical advice.
What is the half-life of BPC-157?
Research reports an approximate half-life of 30 minutes for BPC-157. Half-life informs how frequently a compound is studied; it is not a dosing instruction.
How should BPC-157 be stored?
Refrigerated; stable at room temp for short shipping windows Once reconstituted: Refrigerated 2-8°C; use within ~30 days (about 30 days). This is general storage information, not medical advice.
What is BPC-157 commonly studied alongside?
In the research literature BPC-157 is often discussed together with tb 500. Co-occurrence in studies is not an endorsement of any combination.
Related compounds
Keep your protocol, doses, and vials in one place.
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